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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
21.52
Human Site:
S554
Identified Species:
31.56
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
S554
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
G
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
S554
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
G
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
S554
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
G
Dog
Lupus familis
XP_533285
610
69806
A554
T
V
E
K
E
E
E
A
E
P
E
E
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
S553
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
V
Rat
Rattus norvegicus
P35565
591
67236
S553
K
L
E
E
K
Q
K
S
D
A
E
E
D
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
S557
K
H
G
E
K
Q
K
S
D
A
E
E
E
V
G
Chicken
Gallus gallus
NP_001025791
599
68090
N556
K
L
E
E
K
Q
K
N
D
A
D
I
G
S
A
Frog
Xenopus laevis
NP_001080326
611
69964
P567
E
E
S
G
K
Q
K
P
K
Q
D
E
E
E
G
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
A544
E
E
A
E
E
E
E
A
K
D
E
E
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
K374
K
D
E
E
E
A
K
K
A
S
D
K
D
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
A570
E
N
A
E
Q
Q
S
A
N
S
S
Q
S
S
A
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
E529
E
D
E
D
E
E
G
E
K
A
E
E
E
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
L388
G
D
D
E
D
D
D
L
E
D
E
E
D
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
A493
F
G
G
K
K
A
A
A
P
V
E
K
K
K
P
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
P465
F
H
N
E
R
E
S
P
N
P
F
D
R
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
20
N.A.
93.3
100
N.A.
73.3
60
33.3
20
N.A.
33.3
N.A.
13.3
26.6
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
100
N.A.
80
73.3
53.3
53.3
N.A.
60
N.A.
53.3
60
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
13
7
25
7
50
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
7
7
7
7
7
0
44
13
19
7
44
19
0
% D
% Glu:
25
13
57
75
25
25
13
7
13
0
69
69
19
13
19
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
7
13
7
0
0
7
0
0
0
0
0
7
32
38
% G
% His:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
7
% I
% Lys:
50
0
0
13
57
0
57
7
19
0
0
13
13
7
0
% K
% Leu:
0
38
0
0
0
0
0
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
0
7
13
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
7
13
0
0
7
0
7
% P
% Gln:
0
0
0
0
7
57
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
13
38
0
13
7
0
7
19
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
7
0
0
0
7
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _